Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes

Diabetes. 2008 Jul;57(7):1774-83. doi: 10.2337/db07-1769.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptor Proteins, Signal Transducing / metabolism
  • Animals
  • Calcium / metabolism
  • Diabetes Mellitus, Type 2 / enzymology*
  • Diglycerides / metabolism
  • Enzyme Activation
  • Humans
  • Insulin / metabolism*
  • Insulin Receptor Substrate Proteins
  • Insulin Resistance*
  • Insulin Secretion
  • Insulin-Secreting Cells / cytology
  • Insulin-Secreting Cells / enzymology*
  • Liver / enzymology*
  • Mice
  • Mice, Knockout
  • Mice, Transgenic
  • Muscle, Skeletal / enzymology*
  • Phosphorylation
  • Protein Kinase C / chemistry
  • Protein Kinase C / metabolism*
  • Signal Transduction

Substances

  • Adaptor Proteins, Signal Transducing
  • Diglycerides
  • IRS1 protein, human
  • Insulin
  • Insulin Receptor Substrate Proteins
  • Irs1 protein, mouse
  • Protein Kinase C
  • Calcium