Bacillus subtilis spores germinate in the chicken gastrointestinal tract

Appl Environ Microbiol. 2008 Aug;74(16):5254-8. doi: 10.1128/AEM.00580-08. Epub 2008 Jun 27.

Abstract

A number of poultry probiotics contain bacterial spores. In this study, orally administered spores of Bacillus subtilis germinated in the gastrointestinal (GI) tracts of chicks. Furthermore, 20 h after spores were administered, vegetative cells outnumbered spores throughout the GI tract. This demonstrates that spore-based probiotics may function in this host through metabolically active mechanisms.

MeSH terms

  • Administration, Oral
  • Animal Feed / microbiology
  • Animals
  • Bacillus subtilis / genetics
  • Bacillus subtilis / growth & development*
  • Chickens
  • Colony Count, Microbial
  • Food Microbiology*
  • Gastrointestinal Tract / microbiology*
  • Probiotics*
  • RNA, Bacterial / biosynthesis
  • Reverse Transcriptase Polymerase Chain Reaction
  • Spores, Bacterial / genetics
  • Spores, Bacterial / growth & development
  • Time Factors

Substances

  • RNA, Bacterial