The impact of a population-based multi-factorial lifestyle intervention on changes in long-term dietary habits: the Inter99 study

Prev Med. 2008 Oct;47(4):378-83. doi: 10.1016/j.ypmed.2008.05.013. Epub 2008 Jun 4.


Objective: To evaluate the effectiveness of a population-based multi-factorial lifestyle intervention on long-term changes in dietary habits compared to a non-intervention control group.

Methods: The study was a randomized controlled lifestyle intervention study, Inter99 (1999-2006), Copenhagen, Denmark, using a high-risk strategy. Participants in the intervention group (n=6 091) had at baseline a medical health-examination and a face-to-face lifestyle counselling. Individuals at high risk of ischemic heart disease were repeatedly offered both individual and group-based counselling. The control group (n=3 324) was followed by questionnaires. Dietary habits were measured by a validated 48-item food frequency questionnaire and changes were analyzed by multilevel analyses.

Results: At the 5-year follow-up the intervention group compared to the control group had significantly increased their intake of vegetables (men: net-change: 23 g/week; p=0.04; women: net-change: 27 g/week; p=0.005) and decreased the intake of highly saturated fats used on bread and for cooking (men: OR=0.59 (0.41-0.86); women: OR=0.42 (0.30-0.59)). Significant effects on fruit and fish intake were found at the 3-year follow-up but the effect attenuated at the 5-year follow-up.

Conclusion: A population-based multi-factorial lifestyle intervention promoted significant greater beneficial long-term dietary changes compared to the control group, especially the intake of vegetables and saturated fat was improved.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Denmark
  • Dietary Fats
  • Directive Counseling*
  • Energy Intake*
  • Feeding Behavior*
  • Female
  • Follow-Up Studies
  • Fruit
  • Humans
  • Life Style*
  • Male
  • Middle Aged
  • Treatment Outcome
  • Vegetables


  • Dietary Fats