No Difference in Insulin Resistance and Lipid Levels Between Controls and Adolescent Subjects Who Later Develop Psychosis

Schizophr Res. 2008 Sep;104(1-3):31-5. doi: 10.1016/j.schres.2008.05.021. Epub 2008 Jun 30.

Abstract

Type 2 diabetes and dyslipidemias co-occur frequently with psychoses, but it is not known how common they are in adolescents who later develop psychosis. We investigated waist circumference, blood glucose, lipid and insulin levels and insulin resistance in the Northern Finland 1986 Birth Cohort at the age of 15/16 (N=5410). The Social Insurance Institute register and the Finnish Hospital Discharge Register were used to find the participants who developed psychosis (N=21), and they were compared with other participants. There were no differences in the cardiometabolic variables, suggesting that psychotic episode is not preceded by glucose and lipid metabolism disturbances.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Blood Glucose / metabolism
  • Catchment Area, Health
  • Finland / epidemiology
  • Health Behavior
  • Hospitalization
  • Humans
  • Insulin Resistance / physiology*
  • Life Style
  • Lipoproteins / blood*
  • Psychotic Disorders / blood*
  • Psychotic Disorders / epidemiology*
  • Psychotic Disorders / rehabilitation
  • Registries
  • Schizophrenia / blood
  • Schizophrenia / epidemiology
  • Young Adult

Substances

  • Blood Glucose
  • Lipoproteins