Therapeutic challenges in the management of gout in the elderly

Geriatrics. 2008 Jul;63(7):13-8, 20.


Gout is the most common inflammatory arthritis in the elderly population. Management in the elderly requires special consideration. Physiologic changes associated with aging and co-morbidities make the elderly prone to adverse effects of drugs otherwise successfully used in younger counterparts. Use of colchicine, non-steroidal anti-inflammatory drugs, and urate-lowering therapies may be restricted in those with limited renal reserve. Corticosteroids are safe alternatives for short-term use in acute gout. Elderly patients need laboratory monitoring for side effects more frequently than usual. Non-pharmacologic measures such as dietary modifications, regular exercise, and ice therapy should be considered vital adjunctive treatments. A brief review of future therapies is also discussed.

Publication types

  • Review

MeSH terms

  • Aged
  • Female
  • Geriatrics*
  • Gout / classification
  • Gout / diagnosis
  • Gout / drug therapy*
  • Gout Suppressants / adverse effects
  • Gout Suppressants / therapeutic use*
  • Humans
  • Male


  • Gout Suppressants