New qnr gene cassettes associated with superintegron repeats in Vibrio cholerae O1

Emerg Infect Dis. 2008 Jul;14(7):1129-31. doi: 10.3201/eid1407.080132.


A novel qnr determinant emerged in ciprofloxacin-resistant Vibrio cholerae O1 from the Amazon region of Brazil. This qnrVC1 was in a typical class 1 integron. Its attC showed 89% identity with V. parahaemolyticus superintegron repeats. Analysis showed V. cholerae O1 carrying qnrVC2 associated with a V. cholerae superintegron repeat.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics*
  • Cholera / genetics*
  • Drug Resistance, Bacterial / genetics*
  • Humans
  • Integrons / genetics
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Quinolones / pharmacology
  • Sequence Analysis, DNA
  • Vibrio cholerae O1 / drug effects
  • Vibrio cholerae O1 / genetics*


  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Quinolones

Associated data

  • GENBANK/EU436855