Further to some reminders concerning terminology and resorption, this article presents the full denture prosthetic treatment for two patients with total edentation and a prognathic malocclusion. The first case presents a tridimensional symptomatology, described by: a progeny; a voluminous mandibular terrain; a concave profile; a rather closed mandibular angle; a mandible ridge which circumscribes the upper jaw; The particularities of the prosthetic treatment in this case are: a lowering of the posterior occlusal plane; a mounting of the teeth in a limited external position, that is to say, the maxillary lingual cuspids and the mandibular mesio-distal groove on the inter-crest line; the mandibular incisors and cuspids placed with a lingual inclination to obtain an edge-to-edge occlusal contact. The second case is of vertical symptomatology type, described by: a macrogeny; a moderate concavity of the profile; a very marked increase of the vertical dimension; an open mandibular angle; a short ramus; a long mandibule; a very marked overjet between the anterior crests. The particularities of the prosthetic treatment for this case are: a posterior teeth placement, avoiding cross-bite position, taken into account the strong convergence of the intercrest lines; a strong lingual inclination of the mandibular incisors and cuspids, in order to obtain an edge-to-edge occlusal contact. In the light of these two specific cases, emphasis is placed on the particularities of the treatment and on the teeth placement proposed in order to avoid any cross-bite teeth mounting.