Hypoxis hemerocallidea--not merely a cure for benign prostate hyperplasia

J Ethnopharmacol. 2008 Oct 28;119(3):593-8. doi: 10.1016/j.jep.2008.05.027. Epub 2008 Jul 7.

Abstract

The use of Hypoxis hemerocallidea Fisch. and C.A. Mey. (Hypoxidaceae) extracts for ailments other than benign prostate hyperplasia (BPH) is now a reality. The whole extract, the phytosterols, as well as the major constituents it contains (hypoxoside, and its active derivative rooperol) are now finding new applications in the area of anti-oxidants, anti-inflammatories, anti-diabetics, anti-convulsants, inhibitors of drug marker substances and new evidence is presented of activity against cancerous and premalignant cancer cells. In addition, the over-the-counter (OTC) trade has undergone enormous expansion.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Anticonvulsants / pharmacology
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Antioxidants / pharmacology
  • Humans
  • Hypoglycemic Agents / pharmacology
  • Hypoxis / chemistry*
  • Male
  • Nonprescription Drugs
  • Phytosterols / chemistry
  • Phytosterols / isolation & purification
  • Phytosterols / pharmacology
  • Phytotherapy*
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Prostatic Hyperplasia / drug therapy*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Anticonvulsants
  • Antineoplastic Agents, Phytogenic
  • Antioxidants
  • Hypoglycemic Agents
  • Nonprescription Drugs
  • Phytosterols
  • Plant Extracts