Quality of general movements in term infants with asphyxia

Early Hum Dev. 2009 Jan;85(1):7-12. doi: 10.1016/j.earlhumdev.2008.05.006. Epub 2008 Jul 7.


Background: Perinatal asphyxia may result in a developmental disorder. A recently developed non-invasive tool to investigate brain function at an early age is the assessment of general movements (GMs).

Aim: To evaluate relationships between perinatal risk factors and the quality of GMs in the neonatal period and at 3 months in term newborns with asphyxia in a secondary paediatric setting.

Methods: 64 term (>36 weeks postmenstrual age (PMA)) infants with perinatal asphyxia were studied. GMs were assessed at 'writhing' GM age (38-47 weeks PMA) and at 'fidgety' GM age (48-56 weeks PMA). Pre- and perinatal factors were collected in a standardized way.

Results: Multivariate analysis revealed that DA GMs at 'writhing' age mainly correlated with asphyxia related illness. DA GMs at 'fidgety' age correlated in particular with abnormalities on the neonatal ultrasound scan of the brain.

Conclusion: In secondary paediatric settings GM-assessment especially around 3 months is a valuable tool for the assessment of the integrity of the nervous system in term infants with asphyxia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asphyxia / physiopathology*
  • Female
  • Humans
  • Infant, Newborn
  • Male
  • Movement*
  • Multivariate Analysis