UCSC genome browser: deep support for molecular biomedical research

Biotechnol Annu Rev. 2008;14:63-108. doi: 10.1016/S1387-2656(08)00003-3.


The volume and complexity of genomic sequence data, and the additional experimental data required for annotation of the genomic context, pose a major challenge for display and access for biomedical researchers. Genome browsers organize this data and make it available in various ways to extract useful information to advance research projects. The UCSC Genome Browser is one of these resources. The official sequence data for a given species forms the framework to display many other types of data such as expression, variation, cross-species comparisons, and more. Visual representations of the data are available for exploration. Data can be queried with sequences. Complex database queries are also easily achieved with the Table Browser interface. Associated tools permit additional query types or access to additional data sources such as images of in situ localizations. Support for solving researcher's issues is provided with active discussion mailing lists and by providing updated training materials. The UCSC Genome Browser provides a source of deep support for a wide range of biomedical molecular research (http://genome.ucsc.edu).

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Base Sequence
  • California
  • Chromosome Mapping / methods*
  • Computer Graphics*
  • DNA Mutational Analysis / methods*
  • Molecular Biology / methods
  • Molecular Sequence Data
  • Research Design
  • Sequence Analysis, DNA / methods*
  • Software*
  • Universities
  • User-Computer Interface*