Allele frequencies of 11 X-chromosomal loci in a population sample from Ghana

Int J Legal Med. 2009 Jan;123(1):81-3. doi: 10.1007/s00414-008-0251-5. Epub 2008 Jul 8.


Eleven X-chromosomal short tandem repeats (STRs) from two multiplex PCR approaches (DXS6807, DXS8378, DXS7132, DXS6800, DXS9898, DXS7424, DXS101, DXS7133, HPRTB, DXS8377, and DXS7423), located in four different X-chromosomal linkage groups, were typed in a population sample from Ghana, Africa. After genotyping unrelated men (129) and women (114) from the Ashanti population, forensic efficiency parameters such as polymorphism information content and mean exclusion chance were calculated. A deviation from the Hardy-Weinberg equilibrium could not be found. The investigation of 11 father-daughter and seven mother-son meioses revealed no mutations in any STR analyzed. Our data were compared with European, African-American, and Asian populations from the literature.

MeSH terms

  • Chromosomes, Human, X*
  • DNA Fingerprinting*
  • Female
  • Gene Frequency*
  • Genetics, Population*
  • Ghana
  • Humans
  • Male
  • Polymerase Chain Reaction
  • Tandem Repeat Sequences