[Involuntary lid closure caused by defective healing of facial paralysis and its treatment with botulinum toxin]

Klin Monbl Augenheilkd. 1991 Apr;198(4):268-70. doi: 10.1055/s-2008-1045963.
[Article in German]


Unvoluntary lidclosure with movement of the mouth is not so rare in aberrant regeneration of nerve fibers after Bell's palsy. There was no therapy until now. 10 patients with this disease were treated with botulinum-toxin injections into the orbicularis muscle. For an average time of 11 weeks after injection there was a complete absence of synkinesis, followed by a time of 9 weeks of less complaints. Thus 2-3 injections might be sufficient treatment within a year. Complications worth mentioning, especially due to the reduced force of lidclosure, were not observed.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Blepharospasm / drug therapy
  • Blepharospasm / etiology*
  • Botulinum Toxins / administration & dosage*
  • Eyelids / innervation
  • Facial Nerve / drug effects*
  • Facial Paralysis / complications*
  • Facial Paralysis / drug therapy
  • Female
  • Humans
  • Injections, Intramuscular
  • Male
  • Middle Aged
  • Nerve Regeneration / drug effects*


  • Botulinum Toxins