The fallacies of the lipid hypothesis

Scand Cardiovasc J. 2008 Aug;42(4):236-9. doi: 10.1080/14017430801983082.


Most researchers to-day consider that a high intake of saturated fat and elevated LDL cholesterol are the most important causes of atherosclerosis and coronary heart disease. The lipid hypothesis has dominated cardiovascular research and prevention for almost half a century although the number of contradictory studies may exceed those that are supportive. The harmful influence of a campaign that ignores much of the science extends to medical research, health care, food production and human life. There is an urgent need to draw attention to the most striking contradictions, many of which may be unknown to most doctors and researchers.

Publication types

  • Review

MeSH terms

  • Atherosclerosis / etiology*
  • Atherosclerosis / prevention & control*
  • Cholesterol, LDL / adverse effects*
  • Cholesterol, LDL / blood
  • Coronary Disease / prevention & control*
  • Fatty Acids / adverse effects*
  • Fatty Acids / blood
  • Humans


  • Cholesterol, LDL
  • Fatty Acids