A corrected sequence for the predicted protein from the mitogen-inducible TIS11 primary response gene

Oncogene. 1991 Jul;6(7):1277-8.


We previously reported the sequence of a cDNA, TIS11, cloned from TPA-treated Swiss 3T3 cells. Two laboratories have reported sequences for cDNAs that have a region of identity with the TIS11 cDNA, but differ in their 5' and 3' flanking regions. We now report that the original TIS11 cDNA is likely to be a chimeric molecule, and find that the TIS11 gene encodes a protein identical to the TTP and Nup475 genes.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Base Sequence
  • Cell Line
  • Cloning, Molecular
  • Cycloheximide / pharmacology
  • DNA / genetics
  • DNA-Binding Proteins*
  • Immediate-Early Proteins*
  • Mice
  • Molecular Sequence Data
  • Nucleic Acid Hybridization
  • Polymerase Chain Reaction
  • Proteins / genetics*
  • Tetradecanoylphorbol Acetate / pharmacology
  • Tristetraprolin


  • DNA-Binding Proteins
  • Immediate-Early Proteins
  • Proteins
  • Tristetraprolin
  • Zfp36 protein, mouse
  • DNA
  • Cycloheximide
  • Tetradecanoylphorbol Acetate