Skeletal muscle stem cells

Curr Opin Genet Dev. 2008 Aug;18(4):330-6. doi: 10.1016/j.gde.2008.06.005. Epub 2008 Jul 30.

Abstract

In this review we shall discuss recent publications on the heterogeneity of muscle stem cells, signaling pathways that affect their behaviour and regulatory mechanisms that underlie their myogenic fate, with reference to insights provided by work on skeletal muscle formation in the embryo as well as the adult, with the mouse as a model of reference.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Differentiation / genetics
  • Gene Expression Regulation, Developmental
  • Humans
  • Models, Biological
  • Muscle, Skeletal / embryology*
  • Muscle, Skeletal / physiology
  • Myoblasts, Skeletal / cytology
  • Myoblasts, Skeletal / physiology*
  • Satellite Cells, Skeletal Muscle / physiology
  • Signal Transduction / genetics