Acute kidney disease due to immune reconstitution inflammatory syndrome in an HIV-infected patient with tuberculosis

J Int Assoc Physicians AIDS Care (Chic). 2008 Jul-Aug;7(4):178-81. doi: 10.1177/1545109708320683. Epub 2008 Jul 14.

Abstract

This study reports the case of an HIV-infected patient with disseminated tuberculosis who presented an immune reconstitution inflammatory syndrome (IRIS) revealed by an acute kidney disease 45 and 15 days after initiation of antituberculosis therapy and HAART, respectively. Prednisone therapy and the transient withdrawal of HAART improved the renal function and the clinical condition of this patient. All published case reports of IRIS revealed by acute renal failure in HIV-infected patients are also reviewed.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / microbiology*
  • Acute Disease
  • Antiretroviral Therapy, Highly Active
  • Antitubercular Agents / therapeutic use
  • HIV Infections / complications*
  • HIV Infections / drug therapy
  • HIV Infections / immunology
  • Humans
  • Immune Reconstitution Inflammatory Syndrome / complications*
  • Immune Reconstitution Inflammatory Syndrome / immunology
  • Kidney Diseases / etiology*
  • Male
  • Middle Aged
  • Mycobacterium tuberculosis
  • Tuberculosis / complications*
  • Tuberculosis / drug therapy
  • Tuberculosis / microbiology
  • Tuberculosis / pathology

Substances

  • Antitubercular Agents