Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003;4(4):410-5.
doi: 10.1002/cfg.310.

Understanding and Predicting Protein Assemblies With 3D Structures

Affiliations
Free PMC article

Understanding and Predicting Protein Assemblies With 3D Structures

Patrick Aloy et al. Comp Funct Genomics. .
Free PMC article

Abstract

Protein interactions are central to most biological processes, and are currently the subject of great interest. Yet despite the many recently developed methods for interaction discovery, little attention has been paid to one of the best sources of data: complexes of known three-dimensional (3D) structure. Here we discuss how such complexes can be used to study and predict protein interactions and complexes, and to interrogate interaction networks proposed by methods such as two-hybrid screens or affinity purifications.

Similar articles

See all similar articles

Cited by 3 articles

References

    1. Anal Biochem. 1998 Aug 15;262(1):94-6 - PubMed
    1. Trends Genet. 2001 Jun;17(6):346-52 - PubMed
    1. Nature. 2000 Feb 10;403(6770):623-7 - PubMed
    1. Structure. 2000 Jun 15;8(6):669-84 - PubMed
    1. Nat Biotechnol. 2000 Dec;18(12):1257-61 - PubMed

LinkOut - more resources

Feedback