Screening for type 2 diabetes in primary care using a stepwise protocol: the Diabscreen study

Prim Care Diabetes. 2007 Dec;1(4):199-202. doi: 10.1016/j.pcd.2007.09.002. Epub 2007 Oct 30.


Aim: To evaluate a stepwise protocol in opportunistic screening for type 2 diabetes.

Methods: From 2000 to 2001, in 11 Dutch general practices (n=49,229) we invited at-risk patients during usual care for a capillary fasting plasma glucose (cFPG1) measurement. If >6.0 mmol/l, a second sample (cFPG2) was taken on another day, followed by a venous sample (vFPG) if cFPG2>6.0 mmol/l and cFPG1 or 2> or =7.0 mmol/l.

Results: Of 3724 at-risk patients invited for a cFPG1, 3335 (90%) returned for the measurement. Ultimately, in 125 (4%) of them a vFPG was measured. In 101 out of 125 patients the vFPG was > or =7.0 mmol/l, giving a positive predictive value of our protocol of 81%.

Conclusion: A stepwise screening protocol including two subsequent capillary blood glucose measurements from a portable blood glucose meter is well applicable in screening for type 2 diabetes in primary care.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Blood Glucose / analysis*
  • Body Mass Index
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / diagnosis*
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Female
  • Humans
  • Male
  • Mass Screening
  • Middle Aged
  • Predictive Value of Tests
  • Primary Health Care*
  • Risk Factors


  • Blood Glucose