Photon density measured over a cut surface: implications for optical mapping of the heart

Bradley J Roth

doi:10.1109/TBME.2008.925293

Photon density measured over a cut surface: implications for optical mapping of the heart

IEEE Trans Biomed Eng. 2008 Aug;55(8):2102-4. doi: 10.1109/TBME.2008.925293.

Author

Bradley J Roth¹

Affiliation

¹ Department of Physics, Oakland University, Rochester, MI 48309, USA. roth@oakland.edu

PMID: 18632373
DOI: 10.1109/TBME.2008.925293

Abstract

During optical mapping of the heart, the signal represents a weighted average of the transmembrane potential. Researchers sometimes illuminate the epicardium and record over a cut surface. My goal is to compare their signal to the photon density within an intact tissue. Does cutting the tissue affect the signal?

MeSH terms

Algorithms*
Body Surface Potential Mapping / methods*
Computer Simulation
Heart / anatomy & histology*
Heart / physiology*
Humans
Light
Models, Biological*
Photometry / methods*
Radiation Dosage
Radiometry / methods*