[Neurocysticercosis in childhood. II. Computed tomography of 24 patients according to symptomatic and praziquantel treatment]

Arq Neuropsiquiatr. 1991 Mar;49(1):47-51. doi: 10.1590/s0004-282x1991000100007.
[Article in Portuguese]

Abstract

We studied 24 children (15 months to 13 years old) which clinical, CSF and CT findings were compatible to the diagnosis of active neurocysticercosis. The patients were divided into three groups based on the type of treatment: Group I (10 patients) treated with analgesics and/or anticonvulsants; Group II (4 patients) treated with analgesics and or anticonvulsants and corticosteroids; Group III (10 patients) treated with analgesics and/or anticonvulsants, corticosteroids and praziquantel. The first patients CT scan were compared with the sequential CT scan findings (1 month to 5 years). The initial CT scan of 12 patients showed multiple active cysts, in 5 patients an isolated active cyst, in 3 patients partial calcified cysts, in 2 patients cerebral edema and in 2 patients were normal. The final results of the three groups of patients, as far as concern the normalization of CSF abnormalities or calcification of the cysts were the same, no matter the type of treatment applied to them. These results, although the small number of patients, showed that most of the children have good final results, with improvement of clinical symptoms and CT findings. We suggest that neurocysticercosis in children need multicenter study. So, a great number of patients can be followed and better definition can be established on the treatment of neurocysticercosis.

MeSH terms

  • Adolescent
  • Central Nervous System Diseases / complications
  • Central Nervous System Diseases / diagnostic imaging
  • Central Nervous System Diseases / drug therapy*
  • Child
  • Child, Preschool
  • Cysticercosis / complications
  • Cysticercosis / diagnostic imaging
  • Cysticercosis / drug therapy*
  • Humans
  • Infant
  • Praziquantel / therapeutic use*
  • Retrospective Studies
  • Tomography, X-Ray Computed

Substances

  • Praziquantel