Abstract
The discovery of novel conditions for highly beta-stereoselective (>9 : 1) mannosylation of OH-2 of mannosides using a straightforward perbenzylthioglycoside donor has allowed ready assembly of beta-mannosyl oligosaccharides including the repeating trisaccharide motif of the O5 antigen of pathogen Klebsiella pneumoniae.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Carbohydrate Conformation
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Hydroxides / chemistry*
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Mannosides / chemistry*
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Molecular Structure
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Oligosaccharides / chemical synthesis*
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Oligosaccharides / chemistry
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Stereoisomerism
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Thioglycosides / chemistry
Substances
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Hydroxides
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Mannosides
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Oligosaccharides
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Thioglycosides
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hydroxide ion