Comment on "A 3-hydroxypropionate/4-hydroxybutyrate autotrophic carbon dioxide assimilation pathway in Archaea"

Science. 2008 Jul 18;321(5887):342; author reply 342. doi: 10.1126/science.1158879.

Abstract

Berg et al. (Reports, 14 December 2007, p. 1782) reported the discovery of an autotrophic carbon dioxide-fixation pathway in Archaea and implicated a substantial role of this pathway in global carbon cycling based on sequence analysis of Global Ocean Sampling data. We question the validity of the latter claim.

Publication types

  • Comment
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Archaea / classification
  • Archaea / genetics
  • Archaea / metabolism*
  • Autotrophic Processes
  • Bacteria, Anaerobic / classification
  • Bacteria, Anaerobic / genetics
  • Bacteria, Anaerobic / metabolism
  • Carbon Dioxide / metabolism*
  • Hydro-Lyases / chemistry
  • Hydro-Lyases / genetics*
  • Hydro-Lyases / metabolism*
  • Hydroxybutyrates / metabolism*
  • Lactic Acid / analogs & derivatives*
  • Lactic Acid / metabolism
  • Metabolic Networks and Pathways
  • Oceans and Seas
  • Phylogeny
  • Seawater / microbiology*

Substances

  • Hydroxybutyrates
  • Carbon Dioxide
  • 4-hydroxybutyric acid
  • Lactic Acid
  • hydracrylic acid
  • 4-hydroxybutyryl-CoA dehydratase
  • Hydro-Lyases