Poriacosones A and B: two new lanostane triterpenoids from Poria cocos

J Asian Nat Prod Res. Jul-Aug 2008;10(7-8):645-51. doi: 10.1080/10286020802133597.

Abstract

Two new lanostane triterpenoids, poriacosones A (8) and B (9), together with eight known compounds were isolated from the sclerotia of Poria cocos (Schw.) Wolf (Polyporaceae), and identified by spectroscopic analysis, including IR, UV, CD, ESI-TOF-MS, HR-SIMS, 1D-, and 2D-NMR spectra. The structures of the new compounds were established as 3alpha,16alpha-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (8) and 3beta,16alpha-dihydroxy-24-oxolanost-7,9(11)-dien-21-oic acid (9).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Molecular Structure
  • Plant Stems / chemistry
  • Platelet Aggregation Inhibitors / pharmacology
  • Polyporales / chemistry*
  • Rabbits
  • Triterpenes / chemistry*
  • Triterpenes / pharmacology

Substances

  • Platelet Aggregation Inhibitors
  • Triterpenes
  • poriacosone A
  • poriacosone B