BFA effects are tissue and not just plant specific

Trends Plant Sci. 2008 Aug;13(8):405-8. doi: 10.1016/j.tplants.2008.05.010. Epub 2008 Jul 17.


Brefeldin A (BFA) is one of the most popular drugs used by researchers for studies on secretion and endocytosis because it interferes with specific vesicle coat proteins via action on a guanine nucleotide exchange factor. Due to its range of morphological effects on the Golgi apparatus in a variety of plant tissues, we believe that there is more to the BFA response than the primary molecular targets so far identified.

MeSH terms

  • Brefeldin A / pharmacology*
  • Golgi Apparatus / drug effects*
  • Golgi Apparatus / metabolism
  • Golgi Apparatus / ultrastructure
  • Hypocotyl / drug effects
  • Hypocotyl / metabolism
  • Hypocotyl / ultrastructure
  • Microscopy, Electron, Transmission
  • Plant Leaves / drug effects
  • Plant Leaves / metabolism
  • Plant Leaves / ultrastructure
  • Plants / drug effects*
  • Plants / metabolism
  • Plants / ultrastructure


  • Brefeldin A