Bronchiolitis obliterans organizing pneumonia in common variable immunodeficiency syndrome

Chest. 1991 Aug;100(2):552-3. doi: 10.1378/chest.100.2.552.


A 26-year-old woman with common variable immunodeficiency syndrome (CVID) associated with frequent episodes of pneumonia underwent an open lung biopsy showing bronchiolitis obliterans organizing pneumonia (BOOP). Following corticosteroid therapy, there were no further episodes of pneumonia. In addition, there was roentgenographic and gas exchange improvement. This is the first case of BOOP in association with CVID. An immunologic basis of BOOP is postulated.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bronchiolitis Obliterans / etiology*
  • Bronchiolitis Obliterans / pathology
  • Female
  • Granuloma / etiology
  • Granuloma / pathology
  • Humans
  • Immunologic Deficiency Syndromes / complications*
  • Immunologic Deficiency Syndromes / pathology
  • Lung Diseases / etiology
  • Lung Diseases / pathology
  • Pneumonia / etiology*
  • Pneumonia / pathology