Tonically discharging neurons of monkey striatum respond to preparatory and rewarding stimuli

Exp Brain Res. 1991;84(3):672-5. doi: 10.1007/BF00230981.


The behavioral relationships of 396 striatum neurons with regular, tonically elevated discharge rates were studied. While monkeys performed a delayed gonogo task, neurons predominantly located in medial putamen responded with phasic depressions (n = 30) or activations (n = 5) to task-specific stimuli. Particularly effective was an instruction light preparing for movement or no-movement reactions, and an auditory signal associated with reward delivery. Stimuli triggering arm or mouth movements were less effective. The data demonstrate that these usually poorly modulated neurons display context-dependent phasic activity in specific behavioral situations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acoustic Stimulation
  • Animals
  • Caudate Nucleus / cytology
  • Caudate Nucleus / physiology
  • Corpus Striatum / cytology
  • Corpus Striatum / physiology*
  • Macaca fascicularis
  • Movement / physiology
  • Neurons / physiology*
  • Photic Stimulation
  • Putamen / cytology
  • Putamen / physiology
  • Reward