Shuffled domains in extracellular proteins

FEBS Lett. 1991 Jul 29;286(1-2):47-54. doi: 10.1016/0014-5793(91)80937-x.


A comprehensive list of domains in extracellular mosaic proteins is presented. About 40 domains were distinguished by consensus patterns. A subsequent sequence database search recognized these domains in more than 200 extracellular proteins. The results point to a structural network, which may also represent the molecular basis for a complex coordination of various functions within the world of extracellular proteins.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Extracellular Matrix Proteins / chemistry*


  • Extracellular Matrix Proteins