HLA-B*152703, a novel allele, which has arisen by silent mutation in codon 138

H-Y Zou; Z Li; L-H Cheng; S-Z Jin; Z-H Deng

doi:10.1111/j.1399-0039.2008.01099.x

HLA-B*152703, a novel allele, which has arisen by silent mutation in codon 138

Tissue Antigens. 2008 Oct;72(4):405-7. doi: 10.1111/j.1399-0039.2008.01099.x. Epub 2008 Jul 17.

Authors

H-Y Zou¹, Z Li, L-H Cheng, S-Z Jin, Z-H Deng

Affiliation

¹ Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China.

PMID: 18647363
DOI: 10.1111/j.1399-0039.2008.01099.x

Abstract

A novel human leukocyte antigen-B (HLA-B) allele, officially named B*152703, was found during routine high-resolution sequence-based typing in a Chinese potential hematopoietic stem cell transplantation donor. Compared with the HLA-B*152701 sequence, the B*152703 has a silent substitution at position 486(G-->C) in exon 3.

MeSH terms

Adult
Alleles
Amino Acid Substitution / genetics*
Base Sequence
Codon / genetics*
Exons / genetics
HLA-B Antigens / genetics*
Humans
Male
Molecular Sequence Data
Point Mutation
Sequence Alignment

Substances

Codon
HLA-B Antigens

Associated data

GENBANK/EU617016