Tumour-targeted nanomedicines: principles and practice

Br J Cancer. 2008 Aug 5;99(3):392-7. doi: 10.1038/sj.bjc.6604483. Epub 2008 Jul 22.


Drug targeting systems are nanometre-sized carrier materials designed for improving the biodistribution of systemically applied (chemo)therapeutics. Various different tumour-targeted nanomedicines have been evaluated over the years, and clear evidence is currently available for substantial improvement of the therapeutic index of anticancer agents. Here, we briefly summarise the most important targeting systems and strategies, and discuss recent advances and future directions in the development of tumour-targeted nanomedicines.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Drug Delivery Systems*
  • Humans
  • Liposomes
  • Nanomedicine*
  • Neoplasms / drug therapy*
  • Polymers


  • Antineoplastic Agents
  • Liposomes
  • Polymers