Causes and consequences of the evolution of reproductive proteins

Int J Dev Biol. 2008;52(5-6):769-80. doi: 10.1387/ijdb.082577lt.


Proteins involved in reproduction often evolve rapidly, raising the possibility that changes in these proteins contribute to reproductive isolation between species. We review the evidence for rapid and adaptive change in reproductive proteins in animals, focusing on studies in recently diverged vertebrates. We identify common patterns and point out promising directions for future research. In particular, we highlight the ways that integrating the different but complementary approaches of evolutionary and developmental biology will provide new insights into fertilization processes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Biological Evolution*
  • Developmental Biology / methods*
  • Female
  • Fertilization*
  • Genetic Speciation*
  • Germ Cells
  • Humans
  • Male
  • Mice
  • Models, Biological
  • Models, Theoretical
  • Molecular Sequence Data
  • Reproduction