Wegener's granulomatosis presenting as diffuse pulmonary hemorrhage

Intensive Care Med. 1991;17(2):118-20. doi: 10.1007/BF01691435.


A 35-year-old woman experienced diffuse intraalveolar haemorrhage with respiratory distress and acute renal failure. Renal histology and evolution confirmed Wegener's granulomatosis. Early use of immunosuppressive drugs allowed weaning from mechanical ventilation and temporary improvement of the renal failure. A review of the literature emphasizes the rarity of alveolar hemorrhage as an initial symptom of Wegener's granulomatosis and the necessity of aggressive management.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Female
  • Granulomatosis with Polyangiitis / complications*
  • Hemorrhage / etiology*
  • Humans
  • Lung Diseases / etiology*
  • Pulmonary Alveoli