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Case Reports
. 2008 Oct;46(10):3540-3.
doi: 10.1128/JCM.01032-08. Epub 2008 Jul 23.

Detection of Borrelia Bissettii in Cardiac Valve Tissue of a Patient With Endocarditis and Aortic Valve Stenosis in the Czech Republic

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Free PMC article
Case Reports

Detection of Borrelia Bissettii in Cardiac Valve Tissue of a Patient With Endocarditis and Aortic Valve Stenosis in the Czech Republic

Nataliia Rudenko et al. J Clin Microbiol. .
Free PMC article

Abstract

Molecular analysis of a clinical sample confirmed the presence of Borrelia bissettii DNA in cardiac valve tissue from a patient with endocarditis and aortic valve stenosis. This evidence strongly supports the involvement of B. bissettii in Lyme disease in Europe.

Figures

FIG. 1.
FIG. 1.
Phylogenetic analysis of partial flagellin sequences from Lyme disease complex spirochetes and from the cardiac valve tissue of a patient from the Czech Republic with endocarditis. Sequences of the flagellin gene from 12 control species of the B. burgdorferi sensu lato complex were downloaded from GenBank (accession numbers: B. afzelii, D63365; B. andersonii, D83764; B. bissettii, D82857; B. burgdorferi B31, X16933; B. garinii, D82846; B. japonica, D82852; B. lusitaniae, D82856; B. spielmanii, DDQ111034; B. sinica, AB022138; B. tanukii, D82847; B. turdi, D82849; and B. valaisiana, D82854). B. californiensis (GenBank accession number DQ393346) was excluded from the phylogenetic analysis due to the inappropriate size of the flagellin sequence available in GenBank.

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