[Study on chemical constituents in roots and rhizomes of Ligularia duciforms II]

Zhongguo Zhong Yao Za Zhi. 2008 May;33(9):1018-20.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents in roots and rhizomes of Ligularia duciforms.

Method: 90% ethanol extract was isolated and purified by silica gel and sephadex LH-20 column chromatography, the structures of compounds were identified by physicochemical properties and spectral analysis.

Result: Nine compounds were isolated and identified as lupeol (1), isoscopoletin (2), isoline (3), duciformine (4), (2S, 3S, 4R)-sphinganine-(2'R)-delta5',6' (E)-2'-hydroxytetracosanoylamino (5), tetracosanoic acid (6), tetracosanoicacid glyceride (7), (E)-docosyl ferulate (8), (E)-docosyl caffeate (9).

Conclusion: Compounds 1, 2, 5-7 were isolated for the first time from this plant, and the compound 2, 5-7 were isolated firstly from the genus Ligularia.

Publication types

  • English Abstract

MeSH terms

  • Asteraceae / chemistry*
  • Chromatography
  • Coumarins / chemistry
  • Dendrobium / chemistry
  • Fatty Acids / chemistry
  • Magnetic Resonance Spectroscopy
  • Pentacyclic Triterpenes
  • Plant Roots / chemistry*
  • Plants, Medicinal / chemistry
  • Pyrrolizidine Alkaloids / chemistry
  • Rhizome / chemistry*
  • Scopoletin / analogs & derivatives
  • Scopoletin / chemistry
  • Triterpenes / chemistry

Substances

  • Coumarins
  • Fatty Acids
  • Pentacyclic Triterpenes
  • Pyrrolizidine Alkaloids
  • Triterpenes
  • isoline
  • isoscopoletin
  • Scopoletin
  • lupeol
  • lignoceric acid