Influenza vaccination and the activities of plasma acetylcholinesterase and butyrylcholinesterase in institutionalised elderly patients

S J Emam; M S O'Mahony; M El Khatieb; N Edwards; K Woodhouse

doi:10.1016/s0167-4943(98)00113-7

Influenza vaccination and the activities of plasma acetylcholinesterase and butyrylcholinesterase in institutionalised elderly patients

Arch Gerontol Geriatr. 1998 Sep-Oct;27(2):179-85. doi: 10.1016/s0167-4943(98)00113-7.

Authors

S J Emam¹, M S O'Mahony, M El Khatieb, N Edwards, K Woodhouse

Affiliation

¹ Department of Geriatric Medicine, University of Wales College of Medicine, Academic Centre, Llandough Hospital, Penarth CF64 2XX, Wales, UK.

PMID: 18653163
DOI: 10.1016/s0167-4943(98)00113-7

Abstract

Influenza immunisation was given to 30 elderly institutionalised patients (mean age 80 years) and 16 young volunteers (mean age 27 years). Blood was taken at days 0, 2, 7 and 28. Plasma butyrylcholinesterase (BuChE) and acetylcholinesterase (ACHE) activities were measured. The activities of both enzymes were lower in the elderly patients compared to the young volunteers (P<0.001); however, influenza vaccination had no effect on either enzyme, in either age group.