Prescription Opioid Misuse Index: a brief questionnaire to assess misuse

J Subst Abuse Treat. 2008 Dec;35(4):380-6. doi: 10.1016/j.jsat.2008.02.001. Epub 2008 Jul 26.


The Prescription Opioid Misuse Index (POMI) was developed and used in a larger study designed to assess correlates of OxyContin abuse in pain patients prescribed OxyContin, patients treated for OxyContin addiction, and individuals incarcerated for OxyContin-related charges. The POMI was administered to 40 subjects with addiction problems and 34 pain patients who had received OxyContin for pain. Receiver operating characteristic curve analysis indicated that endorsing two or more of six items reliably classified a person as at risk for misuse of their medication. When comparing drug abuse/dependence in subjects classified as misusers or users, significantly more misusers received a diagnosis for alcohol (p < .01), illicit drugs (p < .05), and other prescription medications (p < .05) and reported greater lifetime use of alcohol (p < .002) and illicit drugs (p < .01). No between-group differences were found regarding psychiatric problems. The POMI appears to be a sensitive and specific instrument for identifying patients who misuse opioid medications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alcohol-Related Disorders / complications
  • Analgesics, Opioid / adverse effects*
  • Analgesics, Opioid / therapeutic use
  • Female
  • Humans
  • Illicit Drugs / adverse effects
  • Male
  • Opioid-Related Disorders / diagnosis*
  • Opioid-Related Disorders / etiology
  • Oxycodone / adverse effects*
  • Oxycodone / therapeutic use
  • Pain / drug therapy
  • Prisoners / statistics & numerical data
  • ROC Curve
  • Risk Factors
  • Substance Abuse Detection / methods
  • Substance-Related Disorders / complications
  • Surveys and Questionnaires*


  • Analgesics, Opioid
  • Illicit Drugs
  • Oxycodone