HELIQUEST: a web server to screen sequences with specific alpha-helical properties

Bioinformatics. 2008 Sep 15;24(18):2101-2. doi: 10.1093/bioinformatics/btn392. Epub 2008 Jul 28.


Summary: HELIQUEST calculates the physicochemical properties and amino acid composition of an alpha-helix and screens databank to identify protein segments possessing similar features. This server is also dedicated to mutating helices manually or automatically by genetic algorithm to design analogues of defined features.

Availability: http://heliquest.ipmc.cnrs.fr.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Simulation
  • Databases, Protein
  • Internet
  • Models, Biological
  • Protein Structure, Secondary*
  • Proteins / chemistry
  • Sequence Analysis, Protein / methods*
  • Software*
  • User-Computer Interface


  • Proteins