Effects of silicone gel on burn scars

Burns. 2009 Feb;35(1):70-4. doi: 10.1016/j.burns.2008.04.011. Epub 2008 Jul 30.

Abstract

Aim: To study the efficacy of silicone gel applied to hypertrophic burn scars, in reducing scar interference with normal function and improving cosmesis.

Methods: A randomised, double-blind, placebo-controlled trial involving 38 people with hypertrophic burn scars. Each scar was divided into two segments; silicone gel sheet was applied randomly to one of the two and placebo to the other. Participants were seen again after 1 and 4 months. Their data and wound characteristics were collected using the Vancouver scar scale.

Results: The median age of participants was 22 years (1.5-60 years) and 16 were male; 4 did not attend follow-up and were excluded from the study. There were no significant differences in baseline characteristics. Although after 1 month all scar scale measures were lower in treated areas, only the vascularity scale was significantly different between the two areas. After 4 months, all scale measures were significantly lower in the silicone gel group than in the control group, except for the pain score.

Conclusion: Silicone gel is an effective treatment for hypertrophic burn scars.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Burns / complications
  • Burns / pathology
  • Burns / therapy*
  • Child
  • Child, Preschool
  • Cicatrix, Hypertrophic / pathology
  • Cicatrix, Hypertrophic / therapy*
  • Double-Blind Method
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Silicone Gels / therapeutic use*
  • Treatment Outcome
  • Wound Healing / physiology
  • Young Adult

Substances

  • Silicone Gels