Gastric cancer: pathogenesis, screening, and treatment

Gastrointest Endosc Clin N Am. 2008 Jul;18(3):513-22, ix. doi: 10.1016/j.giec.2008.05.003.


Early gastric cancer is a curable disease regardless of its location, histologic type, genetic changes, or the ethnicity of the patient. To improve the detection rate of early gastric cancer, intensive training of endoscopists and the use of novel endoscopic techniques have been introduced into routine examinations in Japan. In the United States, where most gastric cancer is found in advanced stages, a similar approach should be advocated. Endoscopic resection of high-grade dysplasia is also encouraged in the United States not only for proper diagnosis but also for achieving cure without surgical intervention.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Gastroscopy*
  • Humans
  • Mass Screening* / methods
  • Risk Factors
  • Stomach Neoplasms / diagnosis
  • Stomach Neoplasms / drug therapy
  • Stomach Neoplasms / physiopathology*
  • Stomach Neoplasms / surgery
  • Time Factors