Meniere's disease

Lancet. 2008 Aug 2;372(9636):406-14. doi: 10.1016/S0140-6736(08)61161-7.


Meniere's disease is a chronic illness that affects a substantial number of patients every year worldwide. The disease is characterised by intermittent episodes of vertigo lasting from minutes to hours, with fluctuating sensorineural hearing loss, tinnitus, and aural pressure. Although there is currently no cure, more than 85% of patients with Meniere's disease are helped by either changes in lifestyle and medical treatment, or minimally invasive surgical procedures such as intratympanic steroid therapy, intratympanic gentamicin therapy, and endolymphatic sac surgery. Vestibular neurectomy has a very high rate of vertigo control and is available for patients with good hearing who have failed all other treatments. Labyrinthectomy is undertaken as a last resort and is best reserved for patients with unilateral disease and deafness.

Publication types

  • Review

MeSH terms

  • Diet
  • Diuretics / therapeutic use
  • Endolymphatic Sac / surgery*
  • Female
  • Humans
  • Life Style*
  • Male
  • Meniere Disease / diagnosis
  • Meniere Disease / physiopathology*
  • Meniere Disease / therapy
  • Treatment Failure
  • Vestibular Nerve / surgery*


  • Diuretics