Screening for prostate cancer: U.S. Preventive Services Task Force recommendation statement

Ann Intern Med. 2008 Aug 5;149(3):185-91. doi: 10.7326/0003-4819-149-3-200808050-00008.


Description: Update of the 2002 U.S. Preventive Services Task Force (USPSTF) recommendation statement about screening for prostate cancer.

Methods: The USPSTF evaluated randomized, controlled trials of the benefits of prostate cancer screening; cohort and cross-sectional studies of the psychological harms of false-positive prostate-specific antigen test results; and evidence on the natural history of prostate-specific antigen-detected prostate cancer to address previously identified gaps in the evidence from the 2002 USPSTF recommendation.

Recommendations: Current evidence is insufficient to assess the balance of benefits and harms of screening for prostate cancer in men younger than age 75 years (I statement). Do not screen for prostate cancer in men age 75 years or older (Grade D recommendation).

Publication types

  • Practice Guideline
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Biopsy / adverse effects
  • Biopsy / standards
  • False Positive Reactions
  • Humans
  • Male
  • Mass Screening / methods
  • Mass Screening / psychology
  • Mass Screening / standards*
  • Middle Aged
  • Physical Examination / standards
  • Prostate-Specific Antigen / blood*
  • Prostatic Neoplasms / diagnosis*
  • Prostatic Neoplasms / therapy
  • Risk Assessment


  • Prostate-Specific Antigen