New insights into calcium, dairy and colon cancer

World J Gastroenterol. 2008 Jul 28;14(28):4429-33. doi: 10.3748/wjg.14.4429.


This paper is to review recent information about the relationship of calcium and dairy foods to colon cancer. The review focuses on primary prevention, discusses the potential components in dairy foods that might be anti-neoplastic, reviews the epidemiologic information and describes intervention studies demonstrating efficacy of calcium and vitamin D in reducing colorectal polyp recurrence. Since vitamin D is important in cancer prevention, pertinent data is discussed and potential mechanisms of actions presented. Calcium and vitamin D are important agents for the primary prevention of colorectal neoplasia.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Adenomatous Polyps / prevention & control
  • Animals
  • Calcium / therapeutic use*
  • Colonic Neoplasms / prevention & control*
  • Dairy Products*
  • Disease Models, Animal
  • Humans
  • Vitamin D / therapeutic use


  • Vitamin D
  • Calcium