Nickel-catalyzed cross-coupling reactions of benzylic zinc reagents with aromatic bromides, chlorides and tosylates

Chem Commun (Camb). 2008 Jul 14:(26):3046-8. doi: 10.1039/b803072c. Epub 2008 Apr 24.

Abstract

Benzylic zinc reagents prepared by direct insertion of zinc to benzylic chlorides in the presence of LiCl undergo smooth cross-coupling reactions with aromatic chlorides, bromides and tosylates using Ni(acac)(2) and PPh(3) as a catalyst system.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzyl Compounds / chemistry*
  • Bromides / chemistry*
  • Catalysis
  • Chlorides / chemistry*
  • Nickel / chemistry*
  • Tosyl Compounds / chemistry*
  • Zinc / chemistry*

Substances

  • Benzyl Compounds
  • Bromides
  • Chlorides
  • Tosyl Compounds
  • Nickel
  • Zinc