Recurrent Fisher's syndrome with immunological abnormalities and replicated laterality

Eur Neurol. 1991;31(4):270-2. doi: 10.1159/000116688.


A case of Fisher's syndrome which recurred 10 years apart was reported. Laterality of cranial nerve findings in the initial episode was replicated in the recurrence. Some kind of localized immune sensitization is supposed to play a role in replicating such a laterality. Increased CD4/CD8 ratio and elevated IgE were noted, which suggests immunological behavior in Fisher's syndrome similar to that in Guillain-Barré syndrome.

Publication types

  • Case Reports

MeSH terms

  • Ataxia / physiopathology
  • Functional Laterality
  • Humans
  • Immunoglobulin E / immunology
  • Lymphocyte Subsets / immunology
  • Male
  • Middle Aged
  • Ophthalmoplegia / physiopathology
  • Polyradiculoneuropathy / immunology
  • Polyradiculoneuropathy / physiopathology*
  • Recurrence
  • Reflex, Abnormal / physiology
  • Syndrome


  • Immunoglobulin E