Inhibition of shoot branching by new terpenoid plant hormones

Nature. 2008 Sep 11;455(7210):195-200. doi: 10.1038/nature07272.


Shoot branching is a major determinant of plant architecture and is highly regulated by endogenous and environmental cues. Two classes of hormones, auxin and cytokinin, have long been known to have an important involvement in controlling shoot branching. Previous studies using a series of mutants with enhanced shoot branching suggested the existence of a third class of hormone(s) that is derived from carotenoids, but its chemical identity has been unknown. Here we show that levels of strigolactones, a group of terpenoid lactones, are significantly reduced in some of the branching mutants. Furthermore, application of strigolactones inhibits shoot branching in these mutants. Strigolactones were previously found in root exudates acting as communication chemicals with parasitic weeds and symbiotic arbuscular mycorrhizal fungi. Thus, we propose that strigolactones act as a new hormone class-or their biosynthetic precursors-in regulating above-ground plant architecture, and also have a function in underground communication with other neighbouring organisms.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / drug effects
  • Arabidopsis / genetics
  • Arabidopsis / growth & development
  • Gene Expression Regulation, Plant
  • Lactones / analysis
  • Lactones / chemistry
  • Lactones / metabolism
  • Lactones / pharmacology*
  • Mutation
  • Oryza / drug effects
  • Oryza / growth & development
  • Oryza / metabolism
  • Oryza / parasitology
  • Plant Growth Regulators / analysis
  • Plant Growth Regulators / chemistry
  • Plant Growth Regulators / metabolism
  • Plant Growth Regulators / pharmacology*
  • Plant Roots / parasitology
  • Plant Shoots / drug effects*
  • Plant Shoots / growth & development*
  • Seedlings
  • Terpenes / analysis
  • Terpenes / chemistry
  • Terpenes / metabolism
  • Terpenes / pharmacology*


  • GR24 compound
  • Lactones
  • Plant Growth Regulators
  • Terpenes