Tuberculin skin-test-induced uveitis in the absence of tuberculosis

Graefes Arch Clin Exp Ophthalmol. 1991;229(3):232-6. doi: 10.1007/BF00167874.


A 16-year-old Caucasian girl who showed no evidence of tuberculosis or other systemic disease developed acute panuveitis progressing to bilateral serous retinal detachments following purified protein derivative (PPD) skin testing on two separate occasions separated by an interval of 8 years. Both episodes responded rapidly to steroid therapy. Uveal hypersensitivity to PPD skin testing has been described in the presence of ocular or systemic tuberculosis, Eales' disease, and the Vogt-Koyanagi-Harada syndrome (VKH). Our case, however, suggests that profound uveitis may be precipitated by routine PPD skin testing alone.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Panuveitis / drug therapy
  • Panuveitis / etiology*
  • Prednisone / administration & dosage
  • Retinal Detachment / drug therapy
  • Retinal Detachment / etiology
  • Tuberculin Test / adverse effects*
  • Tuberculosis / diagnosis*


  • Prednisone