General implementation of the ERETIC method for pulsed field gradient probe heads

J Magn Reson. 2008 Oct;194(2):307-12. doi: 10.1016/j.jmr.2008.07.013. Epub 2008 Jul 18.

Abstract

A capacitive coupling between a secondary radiofrequency (rf) channel and the gradient coil of a standard commercially available high resolution NMR spectrometer and probe head is described and used to introduce a low level exponentially damped rf signal near the frequency of the primary rf channel to serve as an external concentration standard, in analogy to the so-called ERETIC method. The stability of this inexpensive and simple to implement method, here referred to as the Pulse Into the Gradient (PIG) approach, is superb over a 14-h period and both gradient tailored water suppression and one-dimensional imaging applications are provided. Since the low level signal is introduced via the pulsed field gradient coil, the coupling is identical to that for a free induction signal and thus the method proves to be immune (within 5%) to sample ionic strength effects up to the 2M NaCl solutions explored here.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer-Aided Design*
  • Equipment Design
  • Equipment Failure Analysis
  • Magnetic Resonance Spectroscopy / instrumentation*
  • Magnetics / instrumentation*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted / instrumentation*
  • Transducers*