Data mining tools for genotype-phenotype correlation

AMIA Annu Symp Proc. 2007 Oct 11:1037.

Abstract

Single Nucleotide Polymorphisms (SNPs) may be the key to diagnosing and treating certain diseases. A preliminary study was conducted at The Ohio State University Medical Center Information Warehouse to correlate such SNPs with a selected group of lab values for cardiology patients. Early results show that data mining tools can be valuable for understanding such correlations, but further refinement of the methodology and data preparation is needed to fully realize such value.

MeSH terms

  • C-Reactive Protein / analysis
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / genetics*
  • Genotype
  • Humans
  • Information Storage and Retrieval*
  • Lipids / blood
  • Phenotype*
  • Polymorphism, Single Nucleotide*

Substances

  • Lipids
  • C-Reactive Protein