Brain abscess caused by Cladophialophora Bantiana in an immunocompetent host: need for a novel cost-effective antifungal agent

Indian J Med Microbiol. Jul-Sep 2008;26(3):271-4. doi: 10.4103/0255-0857.42050.


We report a 53-year-old male who presented with headache, tremor and memory disturbance. Radiological evaluation was suggestive of brain abscess. He underwent gross total excision of the cerebral abscess. The histopathological examination and pus culture was suggestive of brain abscess caused by Cladophialophora bantiana. Authors report a rare case of biopsy and culture proven Cladophialophora bantiana brain abscess in an immunocompetent host. The authors review the relevant literature and current treatment options while emphasizing the need for a cost-effective novel antifungal drug to salvage a subset of patients suffering from this rare but increasingly frequent condition.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Ascomycota / isolation & purification*
  • Brain Abscess / microbiology*
  • Brain Abscess / physiopathology
  • Brain Abscess / surgery
  • Humans
  • Male
  • Middle Aged
  • Mycoses / diagnosis*
  • Mycoses / microbiology
  • Mycoses / physiopathology
  • Mycoses / surgery


  • Antifungal Agents