Abstract
Mild conditions have been developed to achieve Pd(OAc)2-catalyzed regioselective cross-coupling between indoles and potassium aryltrifluoroarylborates in the presence of Cu(OAc)2 in acetic acid at room temperature. A variety of potassium aryltrifluoroborates selectively undergo the direct arylation across indoles and afford 2-aryl indoles in moderate to good yields.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Borates / chemistry*
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Catalysis
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Indoles / chemical synthesis*
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Indoles / chemistry*
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Molecular Structure
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Organometallic Compounds / chemistry*
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Palladium / chemistry*
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Potassium / chemistry*
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Salts / chemistry
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Stereoisomerism
Substances
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Borates
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Indoles
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Organometallic Compounds
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Salts
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cupric acetate
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Palladium
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Potassium