Maternal and neonatal characteristics of extremely low birth weight infants who die in the first day of life

J Perinatol. 2009 Jan;29(1):33-8. doi: 10.1038/jp.2008.112. Epub 2008 Aug 14.


Objective: To determine changes over time in the characteristics of early extremely low birth weight non-survivors (E-ELBW-NS), maternal characteristics and perinatal management, and the documentation of perinatal consultations.

Study design: We conducted a chart review of infants <750 g who died within 24 h divided into two epochs: 1 January 1995 to 31 December 1999 and 1 January 2000 to 31 December 2005. Maternal and neonatal characteristics, delivery room resuscitation, post-resuscitation care, and documentation of resuscitation and perinatal counseling were examined.

Result: A total of 138 infants met inclusion criteria. During Epoch 2, there was an increase in black, small for gestational age infants and prior maternal preterm delivery, and decreased incidences of tocolysis and chorioamnionitis. Also, a trend toward more hemolysis elevated liver enzymes and low platelet syndrome and decreased prenatal care existed. Perinatal consultations increased in both number and quality with time.

Conclusion: There has been a shift in racial distribution toward more black infants in the second epoch perhaps reflecting disparities in care. Otherwise, demographics and management of E-ELBW-NS have changed minimally. There has been a significant improvement in the documentation of perinatal consultations.

MeSH terms

  • Female
  • Humans
  • Infant Mortality / trends*
  • Infant, Extremely Low Birth Weight*
  • Infant, Newborn
  • Male
  • Perinatal Care*
  • Pregnancy
  • Pregnancy Outcome
  • Resuscitation
  • Time Factors